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Buy tretinoin gel 0.025 % in a dilution of 50% benzoyl peroxide to prevent water absorption has shown good skin-lightening ability after 3–6 months, and the effectiveness of retinol/tretinoin gel 0.025% in a dilution of 50% benzoyl peroxide for 12–40 months has been shown to be similar tretinoin cream 0.05% in a dilution of 75% benzoyl peroxide. The difference between tretinoin cream and tretinoin/tretinoin gel 0.05% is the lightening efficacy compared with tretinoin cream 0.05%. The best results are obtained when the product is used in topical formulations that contain 5% and less of an retinoid (4). 2.2 Retinoids available in Europe at present Currently we have a relatively good experience with five retinoids available in the European market. Retinol tretinoin The drug Retinol Tretinoin is approved by the European Commission as a treatment for acne vulgaris. Retinol Tretinoin contains 0.1% retinoic acid as a hydroquinone ester. There are other tretinoins in the market and they are also approved. The only tretinoin we can recommend is Retinox. The most interesting clinical trial results published with Retinox are summarized by the authors of article on subject. The article is a review with data from double-blind randomized controlled trial that compared two types of retinoids in more than 1200 patients with acne vulgaris who had either moderately or severely visible acne. Results showed that Retinox was superior to the other tretinoin products. data from this case-series do not allow any detailed evaluation of its safety or efficacy compared with other retinoid products. The only drawback to Retinox is its high price which in line with its high potency. Retinide/tretinoin Retinide is mainly used for the treatment of advanced stage diseases such as rosacea. Retinide is approved by the German Federal Institute for Drugs, Nature and Food Safety (BfArM), for the treatment of mild to moderate rosacea. The efficacy of topical retinoid is dependent on its chemical structure and the way that it works from the skin. One of characteristics topical retinoids that makes them suitable for this treatment is the fact that their concentrations can be adjusted in a very easy manner. They are usually given by a prescription. As result, topical retinoid is cheaper and therefore for patients, even those who cannot afford prescriptions. In addition to Retinox, a topical retinoid which is in the same category Retin-A, marketed under the name adapalene, which is also available in topical formulations that contain 5% (4). The efficacy of retinol/tretinoin gel 0.025% has not been systematically evaluated, although buy tretinoin gel 05 it has been proven to be a superior product tretinoin/tretinoin gel 0.05%. However, there are reports of retinol gel 0.025% which have demonstrated good efficacy. buy tretinoin gel .025 In a double-blind randomized controlled clinical trial of 6 months duration the efficacy of tretinoin gel 0.5% in combination with a retinoid was about 40% better than retinol gel 15%. Tazarotene gel 1% is an oral retinoid. It a less potent relative candidate for these patients that Tretinoin 20gm $63.34 - $10.56 Per pill have severe acne and may improve the appearance tolerability of Disulfiram 250 mg their acne. The drug is administered orally. It approved for the treatment of rosacea. clinical data for tazarotene is limited and results in the published studies are conflicting - it appears that reduces sebum production. The drug is highly concentrated and Abc online pharmacy discount code so it is difficult expensive to obtain dosage that is well tolerated. A well-known side effect is phototoxic reactions. It used at a dose of 70–75 mg/day. A tazarotene gel 1% solution is available in Europe for skin lightening the treatment of moderate and severe acne, the efficacy of tazarotene has been compared with that of tretinoin. It should be noted that there are data indicate a negative impact of topical tazarotene on sebum production. The only studies that have examined the toxicity or irritation of drug were conducted with topical tazarotene 0.1%. The findings of these studies seem to indicate that it is very safe with no discernible adverse effects. Retinoids/Tazarotene 0.025% can be compounded with other retinoids at the molecular level, thus improving its effectiveness if used in combination with other retinoids.

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